Most microscopes can only illuminate objects down to a certain size before tiny features blur together. This blurring is known as the diffraction limit of light. Super-resolution imaging techniques, ...

In recent years, technologies that allow scientists to study a person's DNA at single-molecule resolution have vastly expanded our knowledge of the human genome, the microbiome, and the genetic basis ...

Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular ...

Cancer cells rely on powerful genetic switches to keep growth genes running at full speed, but that intense activity can damage their own DNA. The resulting breaks are repeatedly repaired, sometimes ...

Schematic showing a single DNA duplex bridging two gold electrodes (yellow) patterned on a silicon nitride substrate (green). The setup allows measurement of electrical conductance as metal ions bind ...

In May 1952, Rosalind Franklin and Raymond Gosling captured Photo 51, a crucial X-ray diffraction image revealing DNA's ...

Researchers extracted DNA from long-dead animals that lived in South Africa during the last ice age, revealing that genetic material lasts longer in hot climates than was previously thought.

Polymerase chain reaction (PCR) is a workhorse for quantifying nucleic acids across a range of applications, including biomanufacturing and clinical research for viral titer, vector copy number, ...

The authors used a combination of super-resolution imaging techniques and liquid pressure flow to fine-tune the stretch ratio of a DNA molecule, improving the lateral resolution of side-by-side ...